Signals to Solutions  

About Us

Douglas A. I. Pippin

B.Sc. degree in Chemistry from Central Connecticut State University in 1996 and Ph.D. in Synthetic Organic Chemistry in 2001 from Dartmouth College under the guidance of Professor Peter A. Jacobi. In 2002, he joined CGI Pharmaceuticals as a senior research scientist where he led high-throughput medicinal chemistry efforts in early lead identification and lead optimization of targeted kinase programs in oncology and autoimmune/anti-inflammatory disease.   In 2005, Dr. Pippin joined Cephalon, Inc. where he continued his work in the investigation of agents for treatment of cellular proliferation and CNS disorders. In 2009, he founded TransSig, Inc.; as its President and CEO, Pippin continues to focus on the discovery, development and marketing of novel multi-target signal transduction modulating agents for the treatment of cellular proliferation disorders in unmet clinical needs. In 2011, he co-founded PuriSpec, LLC, a company focused on the spectrographic analysis and purification of diverse sets of compounds for numerous applications in drug discovery, with the use of supercritical fluid chromatography/mass spectrometry (SFC/MS). Dr. Pippin currently sits on the board of three privately-held biotechnology firms, TransSig, Inc., PuriSpec, LLC, and Theraceutix, LLC. He is an inventor on 32 patents (issued/pending) and an author of 16 scientific publications and review articles.

Core Competencies:
We specialize in chromatographic method development, separation and isolation of chiral and achiral molecules using Supercritical Fluid Chromatography (SFC). We currently use state-of-the-art JASCO SFC equipment for chiral and achiral method development and small molecule isolations. Our capabilitites currently include SFC, GC, LC, LC/MS and NMR, with isolations ranging from 1 mg to multigram quantities. We offer synthetic chemistry, chromatographic and spectroscopic problem-solving and consulting services for non-GMP applications. Our company currently provides solutions to clients in flavors, fragrances, beverages, foods, fine chemical and petrochemical industries. Contact us for your method development and analytical chemistry needs. Price quotes are available on request.

Loaction: Exton, PA, approximately 35 miles west of Philadelphia.  PuriSpec, LLC, is a privately-held company founded in 2011 and operated by Douglas Pippin, Ph.D.  The laboratories are located in the newly renovated Eagleview Corporate Center.
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