Specializing in Chiral and Achiral Chromatographic Separations and Spectroscopic Solutions
Advancing Drug and Chemical Development Processes by Partnering with our Synthesis and Separation Experts
Accelerating Drug Development Through Expert Purification Science
PuriSpec partners with pharmaceutical and biotechnology companies to deliver expert API synthesis support, chiral SFC separations, and scale-up services from process development to commercial manufacturing.
Core Services
Precision Services Across the Drug Development Continuum
Synthesis & Separation Support
Synthetic organic chemistry expertise across diverse target classes — from initial process development through isolation of soluble intermediates and final API candidates.
Learn more →API Scale-Up Services
End-to-end scale support from early-stage process development through validation and commercial manufacturing. Molecular weights 200–550 g/mol across challenging physico-chemical profiles.
Learn more →Chiral SFC Purification
Supercritical Fluid Chromatography is our method of choice for difficult-to-separate chiral intermediates and final products. Proprietary column technology and deep chiral method development expertise.
Learn more →Chromatography Product Support
Technical and marketing development support for new chromatographic separation products. Leveraging our academic collaborations and proprietary chromatography innovations.
Learn more →Expertise & Differentiators
Led by Classically-Trained Natural Products Chemists
Dr. Pippin, co-founder of PuriSpec, brings over 25 years of drug discovery experience covering biologically active molecules. A classically-trained natural products synthetic chemist, Dr. Pippin leads a team of pharmaceutical partners and consultants with decades of practical industry and academic expertise.
- 25+ years drug discovery experience
- Synthetic organic chemistry & chromatography/MS expertise
- Structural elucidation and chiral method development
- Active academic collaborations
SFC: The Preferred Method for Difficult Separations
Supercritical Fluid Chromatography has been and continues to be the preferred method for difficult-to-separate soluble intermediates and final products. Our team's chiral emphasis, combined with proprietary column technology, delivers separation solutions that conventional HPLC cannot.
Ready to Accelerate Your API Development?
PuriSpec is your expert partner for all pre-clinical non-GMP purification and isolation challenges. Our team of experienced scientists is ready to tackle your most demanding separation problems.
Scope of Services
Pre-clinical non-GMP purification & isolation — from process development to commercial scale